Daniel A. Monaco

Partner Philadelphia
daniel.monaco dbr.com
Phone: (215) 988-3312 (215) 988-3312
Fax: (215) 988-2757


Daniel A. Monaco has been a registered patent attorney since 1981, with extensive experience in all aspects of intellectual property law. He has prepared and prosecuted patent applications, primarily in chemistry and biotechnology. Dan has represented major academic and business clients, individuals and startup companies in the Delaware Valley and elsewhere, before the U.S. Patent and Trademark Office and the federal courts. Dan has counseled clients extensively in international patent protection, and has obtained extensive foreign patent protection for a wide variety of clients.

Dan has represented clients in a broad spectrum of life science technologies, from anticancer therapies and biopharmaceuticals to molecular genetics/biology and clinical diagnostics. He has served as an expert witness during biotechnology litigation.

Dan also counsels clients in technology transfer. He has prepared and negotiated numerous agreements involving the licensing of intellectual property rights. He was conductive extensive intellectual property diligence reviews in furtherance of acquisitions and other corporate transactions.

Dan regularly counsels clients on issues of patent validity and freedom to operate.

Dan is the co-author of What the General Practitioner Should Know About Patent Law and Practice, American Law Institute – American Bar Association Committee on Continuing Professional Education.


Dan has represented diverse business and academic clients in matters pertaining to chemistry and chemical engineering. Representative chemical technologies include:

  • High performance coating, chemical formulations, forestry products and industrial chemical processes
  • Polymers and polymer production methods
  • Human and veterinary health care products, particularly pharmaceuticals such as anticancer, antithrombotic and antiviral drugs
  • Methods and compositions for liquid lung ventilation in neonates
  • Dental products; controlled delivery of pharmaceuticals, such as transdermal drug delivery
  • Diagnostic in vivo imaging of tumors and thrombi
  • Metallurgy

Dan represents clients in a broad spectrum of biotechnology applications, such as:

  • Immunology
  • Cancer vaccines, such as genetically engineered antitumor cellular immunogens
  • Oligonucleotide-based therapies
  • Gene therapies, particularly targeted alteration of genes to correct genetic defects
  • Nuclear transfer, cloning and the production of transgenic animals
  • Generation of null mutant transgenic animals as disease models
  • Antibody technologies and therapeutics
  • Genetic engineering of microorganisms and animals
  • Molecular genetic-based diagnostic methods
  • Novel DNA and expressed proteins
  • Peptide drugs, particularly antithrombotic and anticancer drugs
  • Artificial blood substitutes
  • Agrobiotechnology


Chambers USA, Pennsylvania, Intellectual Property (2004–2005, 2008–2009, 2012–2017)

Awards Methodology (www.drinkerbiddle.com/content/awards)

Daniel Monaco is an experienced patent attorney, who has particular expertise across the field of biological and chemical technology. One client notes: ‘The amazing thing about Dan is whenever I call him, no matter the time, he's there and he picks up the phone for whatever I need.’

Chambers USA (2017)

Daniel Monaco concentrates his practice on patents within the biotechnology and chemistry sectors. Sources note he is 'extremely knowledgeable in the area of law and within science.'

Chambers USA (2013)


Bar Admissions

  • New Jersey
  • Pennsylvania
  • U.S. Patent and Trademark Office


  • Wake Forest University School of Law, J.D., 1981
  • University of Pennsylvania, B.A., Biochemistry , 1977


  • American Bar Association
  • American Chemical Society
  • American Intellectual Property Law Association
  • Philadelphia Bar Association